Adaptive Trial Models in Research
Adaptive trial designs are becoming more widely adopted in clinical research due to their ability to adjust to interim results, improving trial efficiency and reducing costs. Recent advancements in adaptive trial models, particularly in oncology and rare diseases, have enabled researchers to modify trial parameters, such as dose levels, patient populations, and endpoints, based on early data. These models allow for quicker decision-making and can accelerate the development of promising therapies. Research has also highlighted the need for robust statistical frameworks to ensure the validity of these trials, enabling flexibility without compromising scientific rigor.
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