Side Effects&Issues in Multicenter Clinical Trials
Side effects are unwanted or unexpected symptoms or sensations that develop after taking a medication. Minor side effects like a headache or dry mouth can occur. Additionally, they can be fatal, such as major bleeding or permanent liver or kidney damage. Drug side effects may potentially impair your ability to drive.
Clinical trials at the late stages are expensive and ineffective. Simple assumptions result in a trial that is underpowered, not properly accounting for variation. The drug supply chain can be quite wasteful. Independent design choices are made for interrelated elements.
- Interacting Design Factors
- Recruitment of patients
- How many facilities are there, how long is the wait, etc.
- Randomization
- Statistical simulation
- The number of patients, ideal analysis model, etc.
- Patient abandonment
- Drug supply
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Side Effects&Issues in Multicenter Clinical Trials Conference Speakers
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